"Everything comes back to mitochondria. All chronic diseases and cancer are the result of damage to this organelle. The science is telling us this." — Professor Thomas Seyfried
Professor Thomas Seyfried, on the episode
Professor Thomas Seyfried is a cancer biologist at Boston College who has spent decades building on the work of Otto Warburg, the German scientist who argued in the 1920s and 30s that cancer is a metabolic disease rooted in the cell's energy system, not a random genetic accident. The pop framing of cancer is that it is a genetic disease driven by DNA mutations, which is why virtually every mainstream treatment targets genes, DNA, and cell division. The operating system Seyfried runs is different: cancer begins when mitochondria, the organelles that generate energy from oxygen inside every cell, become chronically damaged and fall back on ancient fermentation pathways that no longer regulate cell growth. That shift explains not just why cancer cells behave the way they do, but why lifestyle factors like processed carbohydrates, inactivity, poor sleep, and chronic stress are so consequential, and what a person can actually do about it. This protocol pulls the specific diagnostic tools, dietary thresholds, and treatment logic Seyfried lays out for both prevention and active cancer management.
Tactic 01
Professor Thomas Seyfried, The Diary of a CEO
Use the Glucose Ketone Index to Know Where You Actually Stand
The play
Test your glucose and ketones, calculate your index, and see where you land.
Professor Thomas Seyfried says
The Glucose Ketone Index is found by dividing blood glucose converted to millimolar by blood ketone level. Dividing 90 by 18 gives 5, and dividing that by a ketone reading of 0.4 gives a GKI of 12.5, which puts someone in the prevention zone. People should use a device like the Keto Mojo, which can be bought on Amazon for 20 to 30 dollars, to take finger prick readings. People should test what they eat to see where it puts them on the chart.
Try this
Get a glucose and ketone meter, test fasting readings, divide glucose by 18 then by ketones, and note whether you land near the prevention zone.